Opportunity Information: Apply for 7200AA24RFA00001
Ending Neglected Diseases through Operational Research (ENDOR) is a USAID-funded global health opportunity designed to strengthen how neglected tropical disease (NTD) programs solve real implementation problems in endemic countries. USAID plans to make one award under a five-year cooperative agreement (meaning USAID will remain actively involved in guiding and collaborating on the work). The call is issued under NOFO number 7200AA24RFA00001, with questions due by November 6, 2023 at 1:00 PM Washington, DC time, and applications due by December 8, 2023 at 1:00 PM Washington, DC time. The opportunity is listed as discretionary funding in the health category (CFDA 98.001), with eligibility described as unrestricted (open to any type of entity, including consortia, subject to any additional eligibility language in the full notice). USAID expects to make a single award with a ceiling of up to $45,000,000.
The core rationale for ENDOR comes from gaps identified in the WHO 2030 NTD Roadmap Gap Assessment and reinforced through discussions in the broader NTD community, including the WHO NTD Global Partners Meeting. These gaps include weaknesses in disease-specific strategies for mapping and understanding where transmission persists, challenges in monitoring and evaluation systems that can reliably show progress and inform course corrections, limited availability of accurate diagnostics that are practical for field settings, and the need for more sustainable public health and surveillance systems that countries can maintain over time. USAID notes that these issues are routinely encountered by endemic-country programs and implementing partners, including in USAID flagship NTD efforts such as Act East (led by RTI) and Act West (led by FHI360).
A major theme in the ENDOR design is the growing complexity of NTD work as more countries move toward control and elimination. As programs succeed and community-wide mass drug administration winds down, countries face a different set of operational questions: how to prevent resurgence, how to run periodic surveillance that is both affordable and sensitive enough to detect recrudescence, and how to maintain essential NTD services after elimination or control thresholds are reached. ENDOR is positioned as a way to generate practical, program-ready evidence to guide these post-elimination and sustaining-progress strategies, not just publish research findings.
The opportunity is organized around four high-level focus areas. First, ENDOR aims to foster and convene a network of local and international investigators, with explicit attention to including young and mid-career researchers, and to make the process of identifying and prioritizing operational research needs more diverse and equitable. Second, it will define and carry out coordinated research initiatives that USAID and its NTD implementing partners prioritize, specifically targeting barriers and evidence gaps highlighted by the WHO roadmap and the wider NTD community. Third, it will improve the speed and quality of operational research by issuing subawards directly to local and endemic-country institutions, enabling quicker responses to persistent and emerging implementation challenges and translating results into concrete programmatic solutions that endemic countries can apply. Fourth, ENDOR will work collaboratively with the broader NTD donor community to help ensure research support is equitable and aligned with real project needs, reducing duplication and improving coordination across funders.
In practical terms, ENDOR is less about funding stand-alone academic studies and more about building a functioning operational research engine that connects country programs, implementers, and researchers to solve immediate, field-driven problems. It emphasizes strengthening local leadership and institutional capacity through direct subawards, improving the usefulness and turnaround time of evidence, and ensuring research results are converted into changes in guidelines, tools, and implementation approaches that help countries reach and sustain NTD elimination goals through 2030 and beyond.Apply for 7200AA24RFA00001
- The Agency for International Development in the health sector is offering a public funding opportunity titled "Ending Neglected Diseases through Operational Research (ENDOR)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 98.001.
- This funding opportunity was created on Oct 26, 2023.
- Applicants must submit their applications by Dec 08, 2023. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $45,000,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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