NIDCD Research Grants for Translating Basic Research into Clinical Tools (R01- Clinical Trials Optional) | PAR 18 533

Opportunity Information: Apply for PAR 18 533

The NIDCD Research Grants for Translating Basic Research into Clinical Tools (R01 - Clinical Trials Optional) program (Funding Opportunity Number PAR 18 533) is a National Institutes of Health discretionary grant opportunity designed to move promising discoveries from basic research into practical clinical tools that improve human health. The core intent is to support genuinely translational projects where basic scientists partner closely with clinicians and clinical researchers to convert fundamental findings into real-world approaches that can be used in clinical settings. Projects are expected to make a clear, direct connection to a clinical condition within the National Institute on Deafness and Other Communication Disorders (NIDCD) mission space, and the proposed outcomes should be positioned to have tangible clinical impact rather than remaining at a purely mechanistic or exploratory stage.

The scope of supported work is broad as long as it is aimed at translation and will materially affect the diagnosis, treatment, or prevention of communication disorders. In practice, this means applicants should be proposing work that bridges the gap between laboratory insights and tools clinicians can realistically use. The FOA emphasizes that the link to a clinical problem must be explicitly established, and that the deliverables should be practical, clinically relevant products or methods. While the activity is structured as an R01 research project grant, clinical trials are optional under this announcement, meaning applicants may propose studies that include a clinical trial component when appropriate, but a clinical trial is not required for all projects.

Eligibility is expansive and includes many types of organizations that commonly apply for NIH funding. Eligible applicants include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized tribal governments; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education in those categories); for-profit organizations other than small businesses; small businesses; and other entities as allowed under NIH rules. The announcement also highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal government agencies, regional organizations, U.S. territories or possessions, tribal governments other than federally recognized ones, and non-U.S. (foreign) organizations.

Administratively, the funding instrument is a grant, the funding activity category is health, and the CFDA/assistance listing number associated with the opportunity is 93.173. The opportunity was created on December 21, 2017, and the listed original closing date in the provided data is February 22, 2021. The source information provided does not specify an award ceiling or the expected number of awards, indicating that applicants would typically need to consult the full FOA and NIH budget guidance for the relevant year to understand likely award sizes, project period expectations, and any institute-specific funding considerations.

Overall, this FOA is best suited for teams that already have strong basic science findings in hand and a credible translational plan to turn those findings into clinically meaningful tools for communication disorders, with a clear pathway to implementation, validation, and eventual use in real clinical environments.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIDCD Research Grants for Translating Basic Research into Clinical Tools (R01- Clinical Trials Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173.
• This funding opportunity was created on 2017-12-21.
• Applicants must submit their applications by 2021-02-22. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 18 533

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