Opportunity Information: Apply for HT9425 23 ARP CTA

The Department of Defense Autism Research Program (ARP) Clinical Trial Award is a discretionary funding opportunity run through the U.S. Army Medical Research Acquisition Activity (USAMRAA) that is meant to move autism spectrum disorder (ASD) research quickly into real-world testing. The purpose is straightforward: fund the rapid launch and execution of clinical trials that have a strong chance of making a meaningful difference in how ASD is treated or managed. In practice, this means the program is not looking for early laboratory or animal work, but for studies that are ready to be tested in people and that could change clinical or community-based care if the results are positive.

A central feature of the opportunity is its emphasis on alignment with the fiscal year 2023 ARP Clinical Trial Award Areas of Interest. Applicants are strongly encouraged to design their proposed clinical trial around one of these priority topics. If a proposal does not clearly fit an Area of Interest, the application must make a convincing case that the study still tackles an important and significant problem affecting individuals with ASD. This requirement signals that the program is prioritizing focus and relevance, and it expects applicants to show why their trial matters now and how it could improve outcomes for autistic individuals or address unmet needs in care.

The award supports a wide range of clinical trial types, as long as they are genuinely clinical trials and are aimed at treatment or management. Trials can test promising new products, pharmacologic agents such as drugs or biologics, behavioral interventions, medical or assistive devices, clinical guidance approaches, and emerging methods or technologies that could shift practice. The underlying theme is impact: the program is oriented toward interventions or strategies that could be implemented and that would matter for patients, families, clinicians, and systems of care. At the same time, the funding is not meant for preclinical research, so projects that are primarily exploratory, mechanistic, or limited to lab development without a human trial component would not fit this mechanism.

Administratively, the opportunity is listed under Funding Opportunity Number HT9425 23 ARP CTA and falls within the Science and Technology and other Research and Development activity category (CFDA 12.420). The funding can be made through either a grant or a cooperative agreement, indicating that some projects may involve more active involvement or coordination with the funding agency depending on award structure. Eligibility is described as unrestricted, meaning the competition is broadly open to many entity types, though applicants are still expected to review any clarifications in the full opportunity text. The posting date is March 3, 2023, with an original closing date of July 20, 2023. The notice indicates an expectation of about two awards, and the award ceiling is listed as 0, which typically means the ceiling was not specified in the summary field rather than that no funding is available.

Overall, this opportunity is best viewed as a targeted clinical trials program for ASD that is designed to accelerate the testing of interventions with practical potential. It rewards readiness to run a clinical trial, clear alignment with program priorities (or a well-justified alternative), and a credible pathway to improving treatment or management for people with ASD, while explicitly excluding preclinical work from being supported under this award mechanism.

  • The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Autism, Clinical Trial Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on Mar 03, 2023.
  • Applicants must submit their applications by Jul 20, 2023. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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